Hematological diseases (including leukemia, lymphoma, anemia, and coagulation disorders) require long-term chemotherapy and frequent blood sampling. As the primary vascular access, PICC currently lacks standardized blood sampling protocols based on internal volume, and repeated push-pull manipulations may cause hemolysis, catheter occlusion, and infection. This study aims to measure
Conditions
Interventions
Four-cycle push-pull blood sampling via PICC:Simplified push-pull cycle count
Blood sampling using the push-pull technique with 2 aspirations:Blood sampling using the push-pull technique with 2 aspirations
Sponsors
Zhenjiang First People's Hospital (Affiliated People’s Hospital of Jiangsu University)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Hospitalized hematology patients aged >=18 years who meet the diagnostic criteria for hematologic malignancies according to the *Chinese Society of Clinical Oncology (CSCO) Guidelines for the Diagnosis and Treatment of Malignant Hematological Diseases (2024)*, with a single-lumen 4Fr PICC catheter inserted via the right upper extremity, and with physician orders for routine blood tests; 2. PICC catheter with intact function, demonstrating adequate blood return and unobstructed infusion; 3. Absence of PICC-related complications (e.g., infection, thrombosis); 4. Catheter tip positioned at the lower one-third of the superior vena cava or at the junction of the superior vena cava and right atrium, as confirmed by imaging; 5. Voluntary participation in this study with signed informed consent; 6.Morning blood samples collected.
Exclusion criteria
Exclusion criteria: 1.Patients with hypercoagulable status; 2. Patients currently participating in other clinical studies that may interfere with the results of this study; 3. Patients receiving infusion or blood transfusion at the time of blood sampling.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Key Indices in Complete Blood Count:White blood cell count, neutrophil count, red blood cell count, hemoglobin count, platelet count; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time spent on specimen collection;Catheter occlusion rate; | — |
Countries
China
Contacts
Public ContactYuling Feng
Zhenjiang First People's Hospital (Affiliated People’s Hospital of Jiangsu University)
Outcome results
None listed