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3D-printed patient-specific instrumentation-assisted total knee arthroplasty for ankylosed knees in patients with hemophilia: a case series

3D-printed patient-specific instrumentation-assisted total knee arthroplasty for ankylosed knees in patients with hemophilia: a case series

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600126456
Enrollment
Unknown
Registered
2026-06-09
Start date
2026-06-15
Completion date
Unknown
Last updated
2026-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemophilia, end-stage hemophilic arthropathy, hemophilic knee joint ankylosis

Interventions

Hemophilia stiff knee group:None

Sponsors

The Third Affiliated Hospital of Guangzhou University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Meets the diagnostic criteria for hemophilia, confirmed hemophilic arthropathy, with concurrent knee joint stiffness, defined as knee joint active range of motion <= 30°; 2. Knee joint imaging changes meet the modified Arnold-Hilgartner classification of grade IV or above; 3.Underwent unilateral primary TKA with 3D printed PSI assistance at this hospital; 4.Complete perioperative and postoperative follow-up data; 5. Can assist in completing preoperative and postoperative clinical and imaging assessments.

Exclusion criteria

Exclusion criteria: 1. Those who cannot tolerate general anesthesia and surgical treatment; 2. Those with severe heart, liver, kidney, or other major organ dysfunction, malignant tumors, or mental illness who cannot cooperate with treatment and follow-up; 3.Those with a history of surgery on the same knee; 4.Those with incomplete follow-up data and unable to complete clinical outcome assessment; 5. Combine neuromuscular diseases, spinal cord injuries, cerebral infarction, and other diseases affecting the assessment of lower limb function

Design outcomes

Primary

MeasureTime frame
12-Item Short-Form Health Survey;American Knee Society Score;

Secondary

MeasureTime frame
Hip - Knee - Ankle Angle;

Countries

China

Contacts

Public ContactQunqun Chen

The Third Affiliated Hospital of Guangzhou University of Chinese Medicine

chenqunqun718@163.com+86 10 12345678

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 21, 2026