Corneal disease
Conditions
Interventions
DALK:None
DMEK:None
PKP:None
Sponsors
Tianjin Medical University Eye Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18–85 years; 2.any gender/race; 3.fully mobile and cooperative for examinations; 4.Postoperative time: 3 mon to 15 y;
Exclusion criteria
Exclusion criteria: 1.Postoperative intraocular pressure (IOP) = 21 mmHg; 2.history of contact lens or bandage contact lens wear within 3 months postoperatively; 3.history of infectious keratitis within 3 months postoperatively; 4.patients complicated with blepharitis or moderate to severe dry eye; 5.patients with poorly controlled diabetes mellitus (glycated hemoglobin = 7% or fasting blood glucose > 7 mmol/L); 6.patients with a confirmed history of rheumatic immune diseases; 7.history of intraocular medication administration within 3 months postoperatively;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Subbasal corneal nerve fiber density; | — |
Secondary
| Measure | Time frame |
|---|---|
| Density of nerve branches;Activated corneal dendritic cell density;Levels of neurotrophic factors in tear fluid; | — |
Countries
China
Contacts
Public ContactXiaoran Chu
Tianjin Medical University Eye Hospital
Outcome results
None listed