None
Conditions
Interventions
Experimental group:Oral administration of midazolam solution combined with nasal drops of dexmedetomidine
Sponsors
Xi 'an International Medical Center Hospital
Eligibility
Sex/Gender
All
Age
1 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1. Children undergoing magnetic resonance imaging (MRI) examination of a single area with a total examination time of no more than 15 minutes; 2. Age 1-6 years old, gender not restricted; ASA rating I-II; 3. Normal nasal mucosa, without inflammation, injury, nasal congestion or other conditions that affect drug absorption; 4. The legal guardian of the child is willing to participate in this study and signs the informed consent form, being aware of the relevant compensation and insurance policies of the study.
Exclusion criteria
Exclusion criteria: 1. Allergic to the studied drug; 2. Suffering from systemic diseases with severe organ dysfunction; 3. Having inflammatory conditions, mucosal erosion/injury, nasal congestion, nasal polyps, etc. that affect the absorption of drugs in the nasal mucosa; 4. Having a history of intellectual disability or cognitive impairment and being unable to cooperate; 5. The guardian refuses to participate in the study; 6. Other reasons as deemed by the researcher that make further treatment impossible.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of magnetic resonance examination; | — |
Secondary
| Measure | Time frame |
|---|---|
| Children's behavior scores at the time of drug administration;Modified Ramsay sedation score at the beginning of examination;The time from taking the medicine to achieving satisfactory sedation and initiating the examination (T1);Whether remedial sedation has occurred;Inspection time (T2);Parent satisfaction;Awakening time (T3, the time from the end of the examination to the child's spontaneous opening of eyes); | — |
Countries
China
Contacts
Public ContactHongfei Xiong
Xi 'an International Medical Center Hospital
Outcome results
None listed