Oxygen deficiency
Conditions
Interventions
2000m-altitude generations living at high altitude:None
Long-term plains residents:None
2000m altitude migrants from the plains:None
3000m altitude migrants from the plains:None
3000m-altitude generations living at high altitude:None
Sponsors
The First Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1.Age: 18 - 60 years old; 2.There is no history of any diagnosed mental disorders or neurological diseases (such as stroke, epilepsy, dementia, etc.), nor any history of severe head trauma or brain surgery; 3.There are no chronic diseases that may affect cognitive function or cerebral blood flow, such as severe cardiovascular or cerebrovascular diseases, respiratory system diseases, thyroid dysfunction, or hydrocephalus; 4.right handedness; 5.Normal vision and hearing or corrected vision and hearing do not affect the conduct of the experiment; 6.Voluntary participation and signing of the informed consent form;
Exclusion criteria
Exclusion criteria: 1.Pregnant women or women who are breastfeeding; 2.Drugs that may affect cognitive functions or the central nervous system if used for a long time (such as anticholinergic drugs, sedatives, antidepressants, stimulants, etc.); 3.Consumption of alcohol or other psychoactive substances within the last 24 hours; 4.There was insomnia the night before the test. 5.Having participated in other studies involving cognitive tasks or brain function measurements within the past 4 weeks; 6.There are contraindications for fNIRS testing (such as severe skin diseases on the head, allergies to the instrument materials, etc.); 7.Failure to cooperate or lack of seriousness in the cognitive task process; 8.After repeated attempts, one still fails to understand the rules of the cognitive task paradigm.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stop-Signal Paradigm:Go Task Accuracy Rate;Stop-Signal Paradigm: Stop-Signal Failure Rate;Changes in oxyhemoglobin concentration(?HbO);1-back:Criterion;1-back:Reaction Time;1-back:d-prime;1-back:Accuracy;Stop-Signal Paradigm:Go Reaction Time(Go RT);1-back:False Alarm Rate;Stop-Signal Paradigm:Stop-Signal Reaction Time(SSRT);Stop-Signal Paradigm:Stop-Signal Delay(SSD);Deoxyhemoglobin concentration changes(?HHb);1-back:Hit Rate; | — |
Countries
China
Contacts
Public ContactDing Tao
The First Affiliated Hospital of Kunming Medical University
Outcome results
None listed