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The effect of Dexmedetomidine Nasal Spray on Perioperative Sleep Quality in Patients with Lumbar Disc Herniation

The effect of Dexmedetomidine Nasal Spray on Perioperative Sleep Quality in Patients with Lumbar Disc Herniation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600126410
Enrollment
Unknown
Registered
2026-06-09
Start date
2026-06-15
Completion date
Unknown
Last updated
2026-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

prolapse of lumbar intervertebral disc

Interventions

Control group (N group):Group N received no special treatment
Research Group (Group D):Group D was given DEX nasal drops one night before the operation, on the day of the operation and on the first night after the operation. Spray 1 spray into each nostril, hold

Sponsors

The Second Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1.The patient meets the diagnostic criteria of Western medicine and has been confirmed by CT or MRI. 2. Conservative treatment has been ineffective for more than three months; 3. Patients and their families are aware of the purpose and process of this study, cooperate in completing the scale scoring and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients with skeletal spinal stenosis shown by imaging results; 2. Patients who cannot receive nasal administration, such as those who have undergone nasal surgery or suffered trauma; 3. Those who are allergic to this product and its ingredients; 4. Circulatory system disorders: such as hypotension, bradycardia, sinus arrest, etc. 5. Combined with diseases of the immune system, endocrine system or dysfunction of important organs such as the heart, brain, lungs, liver and kidneys; 6. Allergy to relevant anesthetic drugs; 7. Patients who were unable to complete the scale scoring and refused to participate in this study.

Design outcomes

Primary

MeasureTime frame
Pittsburgh Sleep Quality Index (PSQI) score;

Secondary

MeasureTime frame
Postoperative pain score (VAS);Adverse event records (such as nasal irritation, allergies, daytime sleepiness, etc.);The incidence and severity of nausea and vomiting;

Countries

China

Contacts

Public ContactJunpeng Liu

The Second Hospital Of Hebe Medical University

672244464@qq.com+86 137 3012 7607

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 21, 2026