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Formulation Development and Efficacy Evaluation of Mouthwash for Smoking Population

Formulation Development and Efficacy Evaluation of Mouthwash for Smoking Population

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600126399
Enrollment
Unknown
Registered
2026-06-08
Start date
2026-07-10
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral problems in smokers: bad breath, plaque, gums, inflammation, microbial imbalance

Interventions

Experimental group:Mouthwash rinsing intervention

Sponsors

Nankai University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Willing to sign the informed consent form and fill out the medical history questionnaire; 2. Aged between 18 and 60 years, gender is not limited; 3. Smoking history of 2 to 10 years with fewer than 10 cigarettes smoked daily, accompanied by oral problems including halitosis, swollen gums, mild bleeding and gingivitis; 4. Conscious and able to complete mouth rinsing movements; 5. At least 20 evaluable natural teeth shall remain in the oral cavity (excluding third molars); 6.Voluntarily participate in this trial, attend trial re-examinations on schedule and complete all trial procedures; 7. Agree to stop using any other oral care products (such as mouthwash, dental floss or special functional toothpaste of other brands) during the trial and strictly abide by the intervention protocol of the trial.

Exclusion criteria

Exclusion criteria: 1. Women who are pregnant, planning to become pregnant, or breastfeeding; 2. People with chronic diseases including diabetes, transplants, AIDS, heart disease, and infectious diseases; 3. Have used antibiotics within the past 3 months or regularly used chlorhexidine mouthwash; 4. Persons with visible oral ulcers, mucosal damage, severe periodontal disease, fixed orthodontic brackets or removable dentures; 5. Suffering from severe or uncontrolled systemic chronic diseases (including but not limited to diabetes, transplant-related conditions, AIDS, heart disease and infectious diseases); 6. Individuals who have participated in clinical trials, undergone medical or dental surgery, or are receiving ongoing medical or dental treatment within the past month.

Design outcomes

Primary

MeasureTime frame
Gingival Index;Plaque Index;Oral Odor Index;

Secondary

MeasureTime frame
Satisfaction survey;

Countries

China

Contacts

Public ContactLingling Lu

Nankai University

lulingling@nankai.edu.cn+86 22 23503994

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 10, 2026