Post-cesarean section scar
Conditions
Interventions
Control group (no silicone gel with vitamin C ester):None
Observation group (silicone gel with vitamin C ester):None
Sponsors
The Third Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 49 Years
Inclusion criteria
Inclusion criteria: 1. Undergoing primary cesarean section with complete healing of the abdominal surgical incision postoperatively. 2. Female patients aged 18 to 49 years. 3. Willing to comply with follow-up. 4. Having signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Participants currently involved in other interventional clinical trials. 2. Females taking or likely to take medications that may affect outcome assessment, including but not limited to systemic corticosteroids, immunosuppressive agents, or long-term anti-inflammatory drugs. 3. Complicated with diabetes (including type 1 diabetes, type 2 diabetes, gestational diabetes, and other specific types of diabetes), or other diseases affecting incision healing, such as gestational hypertension, body mass index (BMI) > 30 kg/m², etc. 4. Received other anti-scar therapies within one month prior to enrollment, active abdominal infection, abdominal or pelvic tumor, severe or uncontrolled diseases (such as cardiovascular, renal, hepatic, pulmonary or gastrointestinal diseases, malignant tumor, or HIV infection), or previous treatment involving the lower abdominal wall. 5. Known hypersensitivity to silicone preparations or vitamin C derivatives. 6. Other conditions judged by the investigator as inappropriate for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Between-group differences in the magnitude of improvement in Vancouver Scar Scale (VSS) scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Between-group differences in patient satisfaction with scar improvement.;In the observation group, patient satisfaction with scar improvement.;Between-group differences in the magnitude of improvement in Vancouver Scar Scale (VSS) scores and Visual Analogue Scale (VAS) scores for pain and pruritus, as well as scar photographs.;In the observation group, the magnitude of improvement in Vancouver Scar Scale (VSS) scores and Visual Analogue Scale (VAS) scores for pain and pruritus compared with baseline, as well as scar photogr;In the observation group, the magnitude of improvement in Visual Analogue Scale (VAS) scores for pain and pruritus compared with baseline.;In the observation group, the magnitude of improvement in Vancouver Scar Scale (VSS) scores compared with baseline, as well as scar photographs.;AE;Between-group differences in the magnitude of improvement in Visual Analogue Scale (VAS) scores for pain and pruritus.; | — |
Countries
China
Contacts
Public ContactChen Dunjin
The Third Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed