Oral Cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years 2. ASA classification I–III 3. No cognitive impairment prior to surgery (MoCA >= 26) 4. Signed informed consent form
Exclusion criteria
Exclusion criteria: 1. History of delirium or mental illness prior to surgery; 2. Significant hepatic or renal impairment prior to surgery (Child-Pugh Class C or eGFR < 30 ml/min); 3. Use of antipsychotic or sedative-hypnotic medication prior to surgery; 4. Inability to complete a cognitive assessment (e.g. illiteracy, severe visual or hearing impairment); 5. Emergency surgery or repeat surgery; 6. Cancellation of surgery or change in surgical approach; 7. Intraoperative cardiac arrest or other situations requiring resuscitation due to extreme instability of vital signs; 8. Postoperative requirement for mechanical ventilation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of postoperative delirium (POD); | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of dNCR(delayed Neurocognitive Recovery,dNCR);Severity of delirum;incidence of postoperative complication; | — |
Countries
China
Contacts
Hospital of Stomatology, Sun Yat-sen University