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A Prospective Comparative Study on the Incidence of Late-Onset Hypogonadism in Male Occupational Populations Based on a Health Examination Cohort and the Development of a Risk Prediction Model

A Prospective Comparative Study on the Incidence of Late-Onset Hypogonadism in Male Occupational Populations Based on a Health Examination Cohort and the Development of a Risk Prediction Model

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600126375
Enrollment
Unknown
Registered
2026-06-08
Start date
2026-06-08
Completion date
Unknown
Last updated
2026-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Late-onset hypogonadism

Interventions

Public-sector employee group:None
Enterprise manager group:None

Sponsors

Fifth Affiliated Hospital, Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Voluntarily provide written informed consent; 2.Be male; 3.Aged 30–60 years; 4.Be a regular attendee of the health examination center, including either an actively employed public-sector employee or a middle- or senior-level manager in a large enterprise: Specific inclusion criteria for public-sector employees: defined as male employees, either on official establishment or contract-based, who are actively employed in government agencies or public institutions and engaged in administrative, managerial, or professional/technical work. Eligible work units include government agencies (such as administrative departments and Party/government organs) and public institutions (such as hospitals, schools, and research institutes). Eligible positions include administrative management posts, professional/technical posts, and general affairs posts. Eligible rank includes clerk level or above, or positions recognized by the employing unit as management or technical backbone roles. Specific inclusion criteria for enterprise managers: defined as individuals in enterprises who undertake managerial responsibilities or core decision-making responsibilities. Eligible positions include department heads, middle management, and senior management (such as managers and directors), or individuals who meet at least one of the following criteria: directly supervise three or more subordinates, or participate in departmental decision-making or project management. 5.Have full civil capacity and be able to understand the study content;

Exclusion criteria

Exclusion criteria: 1.Have a confirmed diagnosis of hypogonadism caused by congenital, traumatic, surgical, tumor-related, or other similar conditions; 2.Have a history of severe cardiac, hepatic, or renal insufficiency, or severe psychiatric disorders; 3.Have used sex hormones or medications that may affect sexual function within the past 3 months, including opioid analgesics, antidepressants, glucocorticoids, exogenous androgens, or other drugs that may influence sex hormone levels;

Design outcomes

Primary

MeasureTime frame
Incident late-onset hypogonadism during follow-up;

Secondary

MeasureTime frame
Erectile dysfunction status;Baseline prevalence of late-onset hypogonadism;Performance of the LOH risk prediction model;

Countries

China

Contacts

Public ContactTangyuxin

Fifth Affiliated Hospital, Sun Yat-Sen University

mmcct@126.com+86 137 8731 8086

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 21, 2026