Late-onset hypogonadism
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Voluntarily provide written informed consent; 2.Be male; 3.Aged 30–60 years; 4.Be a regular attendee of the health examination center, including either an actively employed public-sector employee or a middle- or senior-level manager in a large enterprise: Specific inclusion criteria for public-sector employees: defined as male employees, either on official establishment or contract-based, who are actively employed in government agencies or public institutions and engaged in administrative, managerial, or professional/technical work. Eligible work units include government agencies (such as administrative departments and Party/government organs) and public institutions (such as hospitals, schools, and research institutes). Eligible positions include administrative management posts, professional/technical posts, and general affairs posts. Eligible rank includes clerk level or above, or positions recognized by the employing unit as management or technical backbone roles. Specific inclusion criteria for enterprise managers: defined as individuals in enterprises who undertake managerial responsibilities or core decision-making responsibilities. Eligible positions include department heads, middle management, and senior management (such as managers and directors), or individuals who meet at least one of the following criteria: directly supervise three or more subordinates, or participate in departmental decision-making or project management. 5.Have full civil capacity and be able to understand the study content;
Exclusion criteria
Exclusion criteria: 1.Have a confirmed diagnosis of hypogonadism caused by congenital, traumatic, surgical, tumor-related, or other similar conditions; 2.Have a history of severe cardiac, hepatic, or renal insufficiency, or severe psychiatric disorders; 3.Have used sex hormones or medications that may affect sexual function within the past 3 months, including opioid analgesics, antidepressants, glucocorticoids, exogenous androgens, or other drugs that may influence sex hormone levels;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incident late-onset hypogonadism during follow-up; | — |
Secondary
| Measure | Time frame |
|---|---|
| Erectile dysfunction status;Baseline prevalence of late-onset hypogonadism;Performance of the LOH risk prediction model; | — |
Countries
China
Contacts
Fifth Affiliated Hospital, Sun Yat-Sen University