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The effect of different anesthetic sedative drugs on postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy

The effect of different anesthetic sedative drugs on postoperative nausea and vomiting in ptieants undergoing laparoscopic cholecystectomy

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600126374
Enrollment
Unknown
Registered
2026-06-08
Start date
2025-01-02
Completion date
Unknown
Last updated
2026-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nausea and vomiting

Interventions

Group P:Induction of anesthesia: Propofol 2mg/kg, bolus time >=30s, (BIS value =30s, (BIS value =1 min, (BIS <=60). Anesthesia maintenance: Remimazolam was administered by pump administration at a rat

Sponsors

Xi'an Aerospace Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Able to understand and sign the informed consent form; 2. Aged 18-80 years, gender is not limited; 3. ASAI-III level; 4. Patients who plan to undergo laparoscopic cholecystectomy under general anesthesia; 5. Not participating in other clinical studies.

Exclusion criteria

Exclusion criteria: 1. Those who are allergic to the general anesthetic used in this study; 2. Those with severe heart, lung, liver, and kidney diseases; 3. Those with systemic infectious diseases; 4. Those who are accompanied by mental illness or have recently taken sedatives; 5. Those who are unwilling to participate in the trial.

Design outcomes

Primary

MeasureTime frame
Incidence of nausea and vomiting within 24 hours after surgery;

Secondary

MeasureTime frame
Incidence of nausea within 24 hours after surgery;;Incidence of vomiting within 24 hours after surgery;;The number of nausea within 24 hours after surgery;The number of vomiting within 24 hours after surgery;Highest Vas pain score;

Countries

China

Contacts

Public ContactLiang Zhang

Department of Anesthesiology, Xi'an Aerospace Hospital

874900233@qq.com+86 132 5970 8740

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 21, 2026