Osteoarthritis
Conditions
Interventions
Observation group:The observation group was given liposomal bupivacaine injection.
Control group:The control group was given ropivacaine hydrochloride injection.
Sponsors
Zhenxiong County People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Meet the surgical indications for total knee arthroplasty and scheduled for unilateral elective surgery; 2. ASA physical status classification Grade I–III; 3. No contraindications to peripheral nerve block; 4. No history of allergy to the medications used in this study; 5. Both patients and their families gave informed consent and signed the informed consent form. 6. Able to cooperate with postoperative pain scoring, functional exercises, and follow-up work.
Exclusion criteria
Exclusion criteria: 1.Combined with severe dysfunction of vital organs such as the heart, liver and kidney; 2.Abnormal coagulation function or infection at the puncture site; 3.Complicated with lower limb neuromuscular lesions and motor dysfunction; 4.History of chronic pain or long-term use of opioids; 5.Unable to cooperate with pain scoring and postoperative follow-up. 6. Has a mental illness or cognitive dysfunction, unable to communicate normally.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score;Dosage of rescue analgesic drugs at 24 h, 48 h and 72 h postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse reaction incidence rate; | — |
Countries
China
Contacts
Public ContactLin Lungang
Zhenxiong County People's Hospital
Outcome results
None listed