gingivitis
Conditions
Interventions
test group:Zhiyan Gingival care (net care) toothpaste
control group:Zhiyan Gingival Care (net care) toothpaste placebo
Sponsors
Hospital of Stomatology, Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Good general health, no serious systemic diseases; 2. Male or female, aged 18-70 years old; 3. There are more than 20 natural teeth, no large area of restoration in the neck of the teeth, no untreated cavities, no severe gingival receding and no serious periodontal disease; 4. Improved Quigley-Hein plaque index >=1.5; 5. Gingival bleeding index >=1.0; 6. Sign informed consent, comply with the rules and requirements of the trial, and complete the 3-month clinical trial.
Exclusion criteria
Exclusion criteria: 1. Currently participating in other oral clinical trials. 2. Currently pregnant or breastfeeding. 3. Untreated caries or severe periodontal disease. 4. Anti-inflammatory, antibacterial or statin drugs should be taken during the trial. 5. Subjects who had used gum health care products in the 4 weeks prior to the trial. 6. Wear full mouth or removable partial denture or orthodontic appliance. 7. More than 6 test subjects with severe staining of the tooth surface. 8. Diabetic patients. 9. Allergy to any component of the study product. 10. Take dietary supplements (such as multivitamins, antioxidants, fish oil, etc.). 11. Use antibiotics within two weeks prior to the start of the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bleeding index (BI);Plaque index (PI); | — |
Secondary
| Measure | Time frame |
|---|---|
| Oral Health Impact Scale (OHIP-14); | — |
Countries
China
Contacts
Public ContactZhenkun Zhu
Hospital of Stomatology, Shandong University
Outcome results
None listed