Postoperative pain
Conditions
Interventions
Group C:Traditional PCA pump (fixed background dose infusion mode)
Group O:Variable rate feedback infusion mode PCA pump
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing laparoscopic radical resection of colorectal cancer under general anesthesia; 2. Aged 18-75 years, gender unlimited, 18.0 kg/m2 <= body mass index (BMI) <= 30.0kg/m2; 3. ASA I - ?; 4. Patients were treated with postoperative patient-controlled intravenous analgesia pump (PCIA); 5. The patients and their families gave informed consent.
Exclusion criteria
Exclusion criteria: 1. Diagnosed mental illness or preoperative inability to communicate due to cognitive impairment or language disorder; 2. Preoperative patients with severe cardiovascular, liver, kidney and other diseases: preoperative patients with severe cardiovascular diseases (such as sick sinus syndrome, high atrioventricular block without pacemaker, severe cardiac insufficiency NYHA ? - ?), or ALT or ast>2 times the upper limit of normal value, or creatinine>the upper limit of normal value, or received dialysis treatment within 28 days before operation; 3. Known allergic reactions to narcotic drugs; 4. Preoperative history of chronic pain or opioid abuse; 5.. Have a history of drug abuse and/or alcohol abuse in recent 3 months, i.e. drinking>2 units of alcohol per day on average (1 unit=360ml of beer with 5% alcohol or 45ml of liquor with 40% alcohol or 150ml of wine; 6. Conversion to laparotomy; 7. Postoperative admission to ICU; 8. Participated in clinical research of other drugs or medical devices in recent 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Opioid consumption; | — |
Secondary
| Measure | Time frame |
|---|---|
| PCA pump related indicators (Total compression times, effective compression times, etc);Pain assessment;Recovery Quality;Adverse Reaction; | — |
Countries
China
Contacts
Public ContactYang Jiangjun
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed