Skip to content

Is Enteral Nutrition with Nighttime Fasting More Effective for Preventing Aspiration and Controlling Blood Glucose

Evaluation of the Application Effectiveness of a Circadian Rhythm-Based Modified Continuous Enteral Nutrition Feeding Regimen in Preventing Aspiration and Regulating Blood Glucose and Nutritional Indicators

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600126335
Enrollment
Unknown
Registered
2026-06-08
Start date
2026-06-11
Completion date
Unknown
Last updated
2026-06-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dysphagia

Interventions

Post-feeding Regimen Adjustment Group:None
Pre-feeding Regimen Adjustment Group:None

Sponsors

Southern Medical University Southern Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Requirement for nasogastric or nasoenteric tube enteral nutrition due to dysphagia, critical illness, or other indicated conditions; 2. Duration of nutritional support >= 7 days; 3. Age >= 18 years; 4. Patients who were hospitalized at Nanfang Hospital of Southern Medical University from January 2022 to January 2025 and did not return for further medical visits thereafter;

Exclusion criteria

Exclusion criteria: 1. Absolute contraindications such as intestinal obstruction, active gastrointestinal bleeding, etc. 2. Severe hepatic or renal dysfunction (Child-Pugh class > B or KDIGO stage 3); 3. Insulin-dependent diabetes mellitus, specific metabolic diseases (e.g., fatty acid oxidation disorders); 4. Pregnancy or lactation; 5. Patients receiving palliative care for tumors or in a terminal state who, in the investigator's judgment, are unsuitable for participation in this study.

Design outcomes

Primary

MeasureTime frame
coefficient of variation (CV) of blood glucose;infection markers;Gastrointestinal tolerance;constipation;The incidence of pulmonary infection;Glycemic control;aspiration;

Secondary

MeasureTime frame
28-day mortality;Length of ICU stay/ total hospital stay;

Countries

China

Contacts

Public ContactYansi Luo

Southern Medical University Southern Hospital

a.yan24@163.com+86 20 6278 6543

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 21, 2026