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Imaging and Pathology Comparison of Small Lung Nodules

Correlation Analysis Between Pathological Features and High-Resolution CT Signs of Pulmonary Ground-Glass Nodules Less Than 2 cm in Diameter

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600126332
Enrollment
Unknown
Registered
2026-06-08
Start date
2026-06-08
Completion date
Unknown
Last updated
2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary ground-glass nodules, atypical adenomatous hyperplasia, lung adenocarcinoma in situ, minimally invasive adenocarcinoma, invasive adenocarcinoma

Interventions

Observation group:None

Sponsors

Meishan City Peoples Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Preoperative high-resolution CT performed at our hospital with a radiological diagnosis of pulmonary ground-glass nodules. 2. The maximum diameter of the nodule was less than 2 cm, and the proportion of ground-glass components (manifested as cloud-like increased density shadows with visible internal vascular and bronchial textures) on thin-slice images was more than 50%. 3. Definitive pathological diagnosis obtained via surgical resection or CT-guided needle biopsy. 4. Complete clinical, imaging, and pathological data available.

Exclusion criteria

Exclusion criteria: 1.CT imaging demonstrates a pure solid nodule, or a part-solid nodule with a solid component ratio greater than 50%; 2.CT imaging is compromised by severe respiratory motion artifacts, metal artifacts, or high noise levels, hindering the assessment of nodule characteristics; 3.Imaging studies or tissue sampling were conducted outside our institution, or patients were referred to external facilities for treatment following their initial workup at our hospital; 4.Before undergoing the current CT scan, the patient had been subjected to any therapeutic intervention for the lung nodule, such as anti-infective treatment, ablation, or surgical resection; 5.It has been confirmed by pathology or clinical follow-up that lymph node metastasis or distant metastasis is present;

Design outcomes

Primary

MeasureTime frame
Pathological subtypes and extent of invasion following surgical resection of pulmonary ground-glass nodules;

Countries

China

Contacts

Public ContactJintao She

Meishan City Peoples Hospital

15520888616@163.com+86 28 3881 7801

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jul 23, 2026