Chronic limb threatening ischemia
Conditions
Interventions
Modeling Group and Validation Group:None
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients who meet the CLTI diagnosis in the 2019 Global Vascular Guidelines for the Treatment of Chronic Limb Threatening Ischemia [8], that is, patients with one of the following clinical symptoms or signs: (1) Ischemic rest pain may be accompanied by ankle-brachial index < 0.4 or ankle blood pressure less than 50mmHg or toe blood pressure less than 30mmHg or transcutaneous partial pressure of oxygen less than 30mmHg. (2) Diabetic Foot Ulcer (DFU); (3) Any lower extremity ulcer with a course of more than two weeks; (4) Gangrene involving any part of the lower limbs or feet; 2. The presence of ischemic lesions in the lower extremity arteries (with varying degrees of stenosis and/or occlusion in large and medium arteries such as the abdominal aorta, iliac artery, femoral artery, and popliteal artery) was confirmed through imaging examinations such as Doppler color Doppler ultrasound, CT angiography (CTA), or magnetic resonance angiography (MRA) of the lower extremity arteries.
Exclusion criteria
Exclusion criteria: 1. Acute limb ischemia (symptoms lasting for 2 weeks or less); Lower extremity ischemia caused by other etiologies, including but not limited to traumatic arterial injury, iatrogenic lower extremity ischemia, aneurysms, etc.; 3. Embolic diseases and chronic non-atherosclerotic vascular conditions of the lower extremities, including but not limited to vasculitis, Buerger's disease, radiation arteritis, etc; 4. Patients who have had or are currently suffering from malignant tumors; 5. Patients who have undergone major amputation before admission.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amputation-Free Survival (AFS); | — |
Secondary
| Measure | Time frame |
|---|---|
| The Area Under Curve(AUC);Accuracy?Precision?Recall?F1-Score; | — |
Countries
China
Contacts
Public ContactLing Hua
The First Affiliated Hospital of Nanchang University
Outcome results
None listed