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C3,4,5 Nerve Root Block versus Interscalene Block Plus Intermediate Cervical Plexus Block on Surgical Stress Response and Muscle Strength in Clavicle Surgery: A Randomized Controlled Trial

C3,4,5 Nerve Root Block versus Interscalene Block Plus Intermediate Cervical Plexus Block on Surgical Stress Response and Muscle Strength in Clavicle Surgery: A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600126305
Enrollment
Unknown
Registered
2026-06-06
Start date
2026-06-10
Completion date
Unknown
Last updated
2026-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Clavicle fracture

Interventions

Experimental group:C3,4, 5 nerve root block was performed. After identification of the target nerves, the needle was advanced via an in-plane approach under ultrasound guidance. A total of 0.5% ropiva
Conrol group:Under ultrasound guidance, perform in-plane needle insertion for interscalene brachial plexus block and middle cervical plexus nerve block, injecting 10ml of 0.5% ropivacaine for each.

Sponsors

Shanghai Sixth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. ASA physical status classification I-III; 2. Scheduled for unilateral clavicular fracture surgery; 3. Aged 18–65 years; 4. BMI ranging from 18 to 35 kg/m².

Exclusion criteria

Exclusion criteria: Patients were excluded if they met any of the following criteria: 1. Infection at the puncture site; 2. Allergy to local anesthetics; 3. Anatomical abnormalities that might affect the block effect; 4. Combined multiple trauma; 5. Scheduled for internal fixation removal surgery (rather than primary clavicular fracture fixation); 6. Moderate to severe respiratory dysfunction; 7. Contralateral diaphragmatic dysfunction; 8. Being pregnant.

Design outcomes

Primary

MeasureTime frame
Index of Consciousness 2;

Secondary

MeasureTime frame
Index of Consciousness 2;Motor blockade effect of the lower limbs (Modified Bromage Score);Grip Strength;perioperative opioid consumption;rescue analgesic medication within 48 hours postoperatively;

Countries

China

Contacts

Public ContactWu Yifan

Shanghai Sixth People's Hospital

niki77@sjtu.edu.cn+86 188 4645 7626

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026