Hashimoto's Thyroiditis
Conditions
Interventions
Selenium group:None
Control group:None
Sponsors
Shanghai Tenth People's Hospital, Tongji University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-78 years old; 2. A confirmed diagnosis of HT; 3. Baseline thyroid peroxidase antibody (TPOAb) levels >40 IU/mL.
Exclusion criteria
Exclusion criteria: 1. Presence of other autoimmune diseases (e.g., Type 1 diabetes mellitus, systemic lupus erythematosus, rheumatoid arthritis, etc.); 2. Severe dysfunction of major organs, including the heart, liver, or kidneys; 3. Pregnant or breastfeeding women; 4. Incomplete clinical data or loss to follow-up; 5. Psychiatric disorders or cognitive impairment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in Thyroid Peroxidase Antibody (TPOAb) Levels rates; | — |
Secondary
| Measure | Time frame |
|---|---|
| Thyroid function parameters, including thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), and free thyroxine (FT4);Immunoglobulin (IgG, IgE);Liver function parameters, including alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), total bilirubin (TBIL), and direct bilirubin (DBIL); | — |
Countries
China
Contacts
Public ContactFei Yu
Department of Nuclear Medicine, Shanghai Tenth People's Hospital, Tongji University
Outcome results
None listed