Postoperative cognitive dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >= 65 years; 2. Elective non-cardiac surgery (general surgery, orthopedics, urology, etc.); 3. ASA grade II-III; 4. Preoperative MMSE >= 24 points; 5. Expected hospital stay >= 5 days; 6. Preoperative PHQ-9 score 5-9 points (mild depression).
Exclusion criteria
Exclusion criteria: 1. History of preoperative delirium or mental disorder; 2. Severe visual impairment or photosensitive disorders; 3. Severe liver or kidney dysfunction; 4. Users of antipsychotic drugs or melatonin preparations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of POD; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sleep quality;Hospitalization period;Change in the degree of depression; | — |
Countries
China
Contacts
Hebei General Hospital