microform cleft lip
Conditions
Interventions
Gold Standard:Currently, the clinical diagnosis of microform cleft lip relies entirely on typical clinical manifestations, including discontinuity of the Cupid's bow on the affected side, elevation of
Index test:High-frequency ultrasound was used to examine the upper lip soft tissue in all subjects, recording the presence or absence of hypoechoic bands, their width, location, and dynamic changes wi
Sponsors
Plastic Surgery Hospital, Academy of Medical Sciences and Peking Union Medical College
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Inclusion Criteria for Case Group: (1) Clinically suspected microform cleft lip, presenting with one or more of the following external abnormalities: discontinuity of the Cupid's bow's peak, elevation of the Cupid's bow's peak, notching of the vermilion mucosa, grooving of the philtral skin, hyperpigmentation of the philtral skin, asymmetry of the bilateral nostrils, etc. (2) No age or gender restrictions. (3) No prior surgical treatment. (4) The patient or their legal guardian agrees to participate in the study and signs the informed consent form. 2. Inclusion Criteria for Control Group: (1) No congenital malformations of the lip and nose. (2) No prior history of surgery or trauma to the lip and nose. (3) No active infection in the lip and nose area. (4) The participant or their legal guardian agrees to participate in this study and signs the informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion Criteria for Case Group: (1) Prior surgery or other treatment on the affected side. (2) Previous history of trauma to the lip and nose area. (3) Presence of other deformities affecting the morphology or function of the lip or nose, beyond the aforementioned abnormalities. (4) Active infection in the lip and nose area within the past 1 month, such as acne, herpes, folliculitis, eczema, etc., or a history of local dermatological treatment within the past 1 month. (5) Inability to cooperate in completing the upper lip ultrasound examination.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Width of the hypoechoic band on ultrasound; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tissue layer of the hypoechoic band on ultrasound; | — |
Countries
China
Contacts
Public ContactWeiyi Sun
Plastic Surgery Hospital, Academy of Medical Sciences and Peking Union Medical College
Outcome results
None listed