Helicobacter pylori infection
Conditions
Interventions
Observation group [According to empirical medication regimen, divided into 5 groups (CA-BQT, DA-BQT, FA-BQT, NA-BQT, HDDT)]:None
Sponsors
The Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. pre-treatment confirmation of H. pylori infection by 13C-UBT (DOB >= 4‰); 2. age >= 18 years; 3. completion of a standardized 14-day eradication regimen; 4. post-treatment 13C-UBT reassessment performed at our center 4–24 weeks after completion of therapy, with eradication success defined as DOB < 4‰.
Exclusion criteria
Exclusion criteria: 1. Competitive acid blockers (P-CABs) within the preceding month; 2. Severe cardiac, hepatic, or renal dysfunction; 3. Psychiatric disorders or cognitive impairment precluding adherence; 4. Follow-up 13C-UBT performed outside the prespecified 4–24-week window.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| H. pylori eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Eradication rate by stratified regimens; | — |
Countries
China
Contacts
Public ContactLi Li
The Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed