Low anterior resection syndrome
Conditions
Interventions
Homologous FMT group:Homologous fecal microbiota transplantation
placebo group:take oral placebo capsules
Sponsors
Department of Colorectal Surgery, the Characteristic Medical Center of PLA Rocket Force
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Patients aged 18-80 years old low rectal cancer. 2.Underwent low anterior resection of rectal cancer and terminal ileostomy, and elective stoma closure was performed 3 to 6 months later. 3.The clinical stage was stage 3 or below. 4.All patients were followed up for more than 6 months. 5.Patients participating in this project voluntarily sign the informed consent form
Exclusion criteria
Exclusion criteria: 1.Combined with other infectious, autoimmune, radiation enteritis and inflammatory bowel disease; 2.Combined with other digestive tract tumor or history of digestive tract tumors; 3.Those who underwent neoadjuvant or postoperative radiotherapy; 4.Those who got anastomotic leakage or severe abdominal infection; 5.Clinical follow-up data is incomplete; 6.Other patients who were not eligible for included.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Low Anterior Resection Syndrome (LARS) Score Questionnaire;Wexner Incontinence Score (Wexner Scale);MSKCC (Memorial Sloan Kettering Cancer Center) Bowel Function Questionnaire;Anorectal Manometry; | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life;Quality of life; | — |
Countries
China
Contacts
Public ContactDing Jianhua
Department of Colorectal Surgery, the Characteristic Medical Center of PLA Rocket Force
Outcome results
None listed