atopic dermatitis (AD)
Conditions
Interventions
Daily Bathing Group:Daily bathing
Weekly Bathing Group:Weekly Bathing
Sponsors
Xi'an Jiaotong University Second Affiliated Hospital
Eligibility
Sex/Gender
All
Age
1 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >= 1 year (applicable to both children and adults); 2.Diagnosed with AD by an outpatient dermatologist; 3.Predominantly mild to moderate: Recommended EASI >=1 or POEM >= 3; 4.Treatment has been relatively stable in the past 2 weeks: No new initiation of systemic treatment; The topical anti-inflammatory regimen is stable (allowing routine moisturizing); 5.The subject and/or the guardian understand and are willing to accept randomization, and are able to complete the 8-week follow-up and diary record (either via mobile device or paper).
Exclusion criteria
Exclusion criteria: 1.The main skin lesions are limited to the hands / venous congestion / contact dermatitis, etc., and it is suspected that it is not dominated by AD; or it is combined with other major skin diseases for evaluation (psoriasis, scabies, etc.); 2.Those who need to initiate or adjust systemic treatment in the near future (such as biologics, JAK inhibitors, cyclosporine, MTX, systemic hormones, etc.); 3.Severe skin infections require systemic antibiotic treatment; 4.Plan to swim or soak in hot springs more than twice a week during the follow-up period; 5.Unable to change the bathing frequency or have extremely poor expected compliance; 6.Pregnant / breastfeeding;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Week 8 POEM Change (?POEM = Week 8 - Week 0); | — |
Secondary
| Measure | Time frame |
|---|---|
| Itch Numeric Rating Scale (Itch NRS);Atopic Dermatitis Control Tool(ADCT);SCORing Atopic Dermatitis(SCORAD);Frequency/dose of topical anti-inflammatory drugs;Dermatology Life Quality Index (DLQI) score;Investigator's Global Assessment (IGA);Eczema Area and Severity Index(EASI);Transepidermal Water Loss(TEWL); | — |
Countries
China
Contacts
Public ContactAn Jingang
Xi'an Jiaotong University Second Affiliated Hospital
Outcome results
None listed