Acute Kidney Injury
Conditions
Interventions
Aki group and non AKI group:None
Sponsors
Affiliated Hospital of Yangzhou University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years, gender not limited; 2. Type of surgery: Cardiac surgery (including but not limited to: coronary artery bypass grafting, valve surgery, aortic dissection surgery, congenital heart disease correction surgery, etc.); 3. Data completeness: Complete perioperative clinical data, including: preoperative baseline creatinine level; intraoperative and postoperative lactate monitoring data (including at least 3 time points from 1h, 2h, 6h, and 12h postoperatively); at least one postoperative creatinine test (within 48 hours or 7 days postoperatively); 4. Informed consent must be signed by the patient or their family, indicating voluntary participation in this study.
Exclusion criteria
Exclusion criteria: 1. Patients diagnosed with chronic kidney disease (CKD) stage 3-5 (eGFR 4 mmol/L within 24 hours preoperatively with a clear cause (e.g., severe infection, shock, liver failure, etc.); 3. Patients with severe liver disease (Child-Pugh class C), end-stage malignant tumors, or coagulation disorders; 4. Patients experiencing severe complications during surgery (e.g., massive hemorrhage, cardiac arrest > 10 min with unsuccessful resuscitation) leading to surgical interruption or death within 24 hours postoperatively; 5. Patients with severely missing clinical data or unable to complete follow-up; 6. Pregnant or lactating patients; 7. Patients participating in other interventional clinical trials concurrently; 8. Patients who refuse to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative acute kidney injury (AKI);Perioperative Lactate Levels; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative hospital stay, intensive care unit (ICU) stay;30-day postoperative mortality; | — |
Countries
China
Contacts
Public ContactChenlong Yi
Affiliated Hospital of Yangzhou University
Outcome results
None listed