FindTrial
Sign In

Regulation of Bile Acid Metabolic Homeostasis by Gut Microbiota Mediates Ovulatory Dysfunction in PCOS: A Matched Case-Control Study

Regulation of Bile Acid Metabolic Homeostasis by Gut Microbiota Mediates Ovulatory Dysfunction in PCOS: A Matched Case-Control Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600126184
Enrollment
Unknown
Registered
2026-06-04
Start date
2026-06-15
Completion date
Unknown
Last updated
2026-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PCOS

Interventions

PCOS patients group:none
Healthy Control group:none

Sponsors

The First Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Female patients with male-factor infertility who are willing to participate as volunteers in this study, as well as PCOS patients attending our center, between May 1, 2026, and April 30, 2029.

Exclusion criteria

Exclusion criteria: 1. Presence of hepatobiliary diseases. 2. Co-infection with pathogens such as Epstein-Barr virus or hepatitis virus. 3. Significant changes in diet or use of antibiotics within the past month. 4. Regular use of probiotic products. 5. Presence of autoimmune diseases. 6. Co-existing severe medical or surgical conditions. 7. Presence of bacterial or fungal infections. 8. Inability to cooperate with the study investigators. 9. Considered by the investigators to be otherwise ineligible for participation.

Design outcomes

Primary

MeasureTime frame
bile acids profiles;—

Countries

China

Contacts

Public ContactYupei Xie

Reproductive Medicine Center,The First Affiliated Hospital of Nanchang University

xieyupei1128@163.com+86 136 9800 4086

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026