Postoperative delirium
Conditions
Interventions
postoperative delirium and non-postoperative delirium:None
Sponsors
Central South University Third Xiangya Hospital Department of Anesthesiology
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18 to 85 years who are scheduled for elective non-cardiac surgery; 2. Surgeries with an anticipated anesthesia duration exceeding 90 minutes; 3. Patients undergoing their first elective surgery requiring general anesthesia with endotracheal intubation during the current hospital admission; 4. American Society of Anesthesiologists (ASA) physical status classification I to III; 5. Subjects who fully understand the benefits and risks of this trial, are willing to participate, and have signed an informed consent form; 6. Communication and cooperation capacity: Conscious patients who are able to understand and cooperate with preoperative cognitive function assessment and the informed consent process.
Exclusion criteria
Exclusion criteria: 1. A history of severe mental disorders (e.g., schizophrenia, acute phase of severe depression) or severe intellectual developmental disability; 2. A history of psychotropic drug abuse; 3. Individuals unable or unwilling to cooperate with questionnaires and clinical examinations; 4.Patients with severe agitation or delirium preoperatively; 5. Patients with a definitive diagnosis of dementia (e.g., Alzheimer's disease, vascular dementia); 6. Patients currently receiving antipsychotic treatment; 7. Presence of cranial bone defects, severe scalp infection, or injury; 8. Patients with severe neurological diseases, such as advanced Parkinson's disease, uncontrolled epilepsy, or severe post-stroke sequelae, which have significantly altered baseline brain electrical activity; 9. Severe hearing or visual impairment preventing completion of cognitive assessment or communication.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EEG features;length of postoperative hospital stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative delirium;PACU-delirium;postoperative sleep quality;postoperative pain score;postoperative adverse outcome; | — |
Countries
China
Contacts
Public ContactXing Liu
Department of Anesthesiology, The Third Xiangya Hospital of Central South University
Outcome results
None listed