Autism Spectrum Disorder (ASD)
Conditions
Interventions
Research Group:Conventional rehabilitation training, BF839 (Bacteroides fragilis 839) mixed probiotic treatment.
Control Group:Conventional rehabilitation training
Sponsors
Beijing Childrens Hospital,Capital Medical University
Eligibility
Sex/Gender
All
Age
2 Years to 5 Years
Inclusion criteria
Inclusion criteria: 1.Age >= 2 years and <= 5 years, regardless of gender; 2.Diagnosis based on the criteria for ASD in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5); 3.The subjects have been consistently receiving rehabilitation training and will be able to maintain regular rehabilitation training for the next six months; 4.No severe congenital diseases, genetic metabolic diseases, other major neurological diseases, or immune system diseases; 5.No severe food allergies or intolerances; 6.No severe infectious diseases in the past month; 7.No history of fecal microbiota transplantation; 8.Voluntarily using the BF839 mixed probiotic preparation.
Exclusion criteria
Exclusion criteria: 1.Children with other unstable or severe heart, lung, liver, kidney, or hematological diseases (including unstable angina, uncontrolled asthma, active gastrointestinal bleeding, cancer, etc.); 2.Children in the probiotic application group who are unable to regularly take probiotics or are unable to attend assessments and follow-ups on time for various reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Other-rating scale scores;Self-rating scale scores; | — |
Countries
China
Contacts
Public ContactLiang Aimin
Beijing Childrens Hospital,Capital Medical University
Outcome results
None listed