Compensated HBV cirrhosis
Conditions
Interventions
HBV-related cirrhosis group:None
CHB non-cirrhotic group:None
Sponsors
Shenzhen Third People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients with chronic hepatitis B who participated in the clinical trial titled "Clinical Study of Recombinant Hepatitis E Vaccine (in Patients with Chronic Hepatitis B)" at this center. 2.Ability to understand and voluntarily sign the written informed consent for this follow-up study.
Exclusion criteria
Exclusion criteria: 1.Presence of any severe medical or psychiatric conditions that, in the investigator’s judgment, may compromise subject safety or interfere with study assessments. 2.Subjects who are unreachable or refuse to participate in this follow-up study. 3.Subjects unable to complete follow-up due to severe underlying diseases (e.g., severe hepatic or renal failure, malignant tumors, immunodeficiency disorders such as AIDS) or with a life expectancy of less than 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HEV-IgG seroconversion rate post-vaccination;Post-vaccination HEV-IgG level (GMC); | — |
Countries
China
Contacts
Public ContactLiao Xuejiao
Shenzhen Third People's Hospital
Outcome results
None listed