Neurocognitive Disorder (NCD)
Conditions
Interventions
Sevoflurane anesthesia group:During the perioperative period, anesthesia was mainly administered using sevoflurane.
Propofol anesthesia group:During the perioperative period, propofol was mainly used to complete the anesthesia regimen.
control:None
Sponsors
The Second People's Hospital of Yibin
Eligibility
Sex/Gender
All
Age
No minimum to 12 Years
Inclusion criteria
Inclusion criteria: 1. Age: Patients aged 0 to 12 years old; 2. The patient meets the American Society of Anesthesiologists grading system I-III; 3. Anesthesia time: 1 to 3 hours; 4. Patients who can communicate and cooperate normally to complete the research process; 5. Patients whose guardians agree to join the group.
Exclusion criteria
Exclusion criteria: 1. Individuals with mental illnesses; 2. Individuals with allergies; 3. Unable to complete cognitive testing scale; 4. Individuals with communication barriers; 5. Those who cannot tolerate anesthesia; 6. Merge patients with severe organ dysfunction; 7. Participate in similar medical research patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of neurocognitive disorders;Significant plasma differential metabolites before and after surgery in the group with neurocognitive disorders following sevoflurane anesthesia;Significant plasma differential metabolites before and after surgery in the group with neurocognitive disorders following propofol anesthesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| anesthesia time;Operation time;Wake-up time;Vital signs (heart rate, blood pressure, respiration, pulse oxygen saturation); | — |
Countries
China
Contacts
Public ContactDeshui Yu
The Second People's Hospital of Yibin
Outcome results
None listed