Stroke
Conditions
Interventions
An Group:Full Cross-domain (Emotion-Cognition-Motor) Adaptive Training
B Group:Integrating Cognitive and Motor Tasks Rehabilitation Training
C Group:Single-dimension Motor Rehabilitation Training
D Group:Conventional Rehabilitation Training
Sponsors
Northwestern Polytechnical University
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meets the stroke diagnostic criteria in the "Key Points for the Diagnosis of Various Cerebrovascular Diseases" and is confirmed by cranial CT or MRI as a first occurrence of cerebral infarction or cerebral hemorrhage; 2. Disease course is 3 months to 1 year (late subacute to recovery phase); 3. Aged 30-80 years; 4. Presence of unilateral hemiplegia, affected side Brunnstrom stage upper limb II-IV or CMSA upper limb stage 2-3; 5. Montreal Cognitive Assessment (MoCA) =26 points or Mini-Mental State Examination (MMSE) =24 points; 6. Patient or legal guardian voluntarily signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Altered consciousness, severe aphasia, visual or auditory impairments, unilateral neglect, agnosia or apraxia, unable to complete tasks according to instructions; 2. Severe cardiovascular diseases (such as heart failure, uncontrolled hypertension); 3. History of neurological diseases such as dementia, Parkinson's disease, epilepsy, or psychiatric disorders; 4. Brainstem/cerebellar lesions, intracranial tumors, arteriovenous malformations; 5. Severe pain in the affected limbs (VAS > 4), severe proprioceptive loss, or significantly limited joint mobility; 6. Expected inability to complete the study protocol or lack of fixed family caregivers; 7. Participation in other clinical trials within 3 months prior to enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Motor function Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Recovery Stage of Gross Motor Function of the Hemiplegic Upper Extremity and Hand;Cognitive;Anxiety;Depression;EEG-Based Motor Imagery Event-Related Synchronization/Desynchronization;Based Cognitive Load Index: Prefrontal Theta/Alpha Power Ratio;EEG-Frontal Alpha Asymmetry Index-Based Emotional/Motivational Tendency;Activities of Daily Living;Brain Region Activation Intensity;Muscle Synergy Index;EEG-fNIRS Coupling; | — |
Countries
China
Contacts
Public ContactWenli Dong
Northwestern Polytechnical University
Outcome results
None listed