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Prospective Cohort Study on Surveillance of High-Risk Populations for Hepatocellular Carcinoma in Hospital and Community Settings Based on the aMAP 3.0 Serological Intelligent Algorithm

Prospective Cohort Study on Surveillance of High-Risk Populations for Hepatocellular Carcinoma in Hospital and Community Settings Based on the aMAP 3.0 Serological Intelligent Algorithm

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600126108
Enrollment
Unknown
Registered
2026-06-03
Start date
2026-06-03
Completion date
Unknown
Last updated
2026-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatocellular carcinoma

Interventions

Participants in Hepatocellular Carcinoma Surveillance:None
Participants with Other Malignant Tumors:None

Sponsors

Southern Medical University Southern Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Subjects for Liver Cancer Surveillance:; 1.1 Patients with cirrhosis due to various liver diseases attending hospitals: Voluntarily sign the informed consent form; Aged 18 years or above, regardless of gender; Diagnosed with cirrhosis; aMAP liver cancer risk score > 50 at enrollment. 1.2 Individuals at intermediate to high risk for liver cancer identified through community screening: Voluntarily sign the informed consent form; Male residents aged 35–64 years and female residents aged 45–64 years; Positive for hepatitis B surface antigen (HBsAg) in community serological testing; aMAP liver cancer risk score > 50 at enrollment. 2. Subjects with Other Malignancies Attending Hospitals: Voluntarily sign the informed consent form; Aged 18 years or above, regardless of gender; Diagnosed with malignancies other than hepatocellular carcinoma (HCC), with an expected survival period of more than 6 months; Have not received any systemic antitumor therapy (such as chemotherapy, targeted therapy, immunotherapy, etc.) for the malignancy at the time of enrollment.

Exclusion criteria

Exclusion criteria: 1.History of liver cancer, liver transplantation, or co-infection with hepatitis C or human immunodeficiency virus (HIV); 2.Pregnancy; 3.Deemed by the investigator as ineligible to participate in the study;

Design outcomes

Primary

MeasureTime frame
Detection Rate of Primary Hepatocellular Carcinoma (HCC);Early-Stage (BCLC Stage 0 and A) Primary Hepatocellular Carcinoma Detection Rate;True Positive Rate and False Positive Rate;

Countries

China

Contacts

Public ContactJinlin Hou

Southern Medical University Southern Hospital

jlhousmu@163.com+86 20 61641941

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026