Chronic Rotator Cuff-Related Shoulder Pain
Conditions
Interventions
C-RCRSP group:Repetitive transcranial magnetic stimulation (rTMS) will be delivered at 10 Hz with a stimulation intensity of 80% of the individual resting motor threshold (RMT). A total of 1,500–3,000
Asymptomatic Rotator Cuff Tear Group:None
Healthy Control Group:None
Sponsors
Beijing Hospital
Eligibility
Sex/Gender
All
Age
30 Years to 70 Years
Inclusion criteria
Inclusion criteria: Chronic Rotator Cuff-Related Shoulder Pain (C-RCRSP) Group Inclusion Criteria: 1.Outpatients recruited from the Department of Rehabilitation Medicine of Peking University Third Hospital and Beijing Hospital; 2.Aged between 30 and 70 years, regardless of sex; 3.Diagnosis of partial-thickness rotator cuff tear confirmed by ultrasonography or magnetic resonance imaging (MRI); 4.Numeric Pain Rating Scale (NPRS) score =2 during shoulder movement, absence of resting pain, and symptom duration longer than 3 months; 5.No history of repetitive transcranial magnetic stimulation (rTMS), neuromodulation therapy, or shoulder injection treatment within the previous 3 months. Asymptomatic Rotator Cuff Tear Group Inclusion Criteria 1.Individuals recruited from health examination centers of Peking University Third Hospital and Beijing Hospital; 2.Aged between 30 and 70 years, regardless of sex; 3.No history of pain in any body region during the previous year; 4.No functional impairment of either shoulder during the previous year; 5.Absence of other shoulder pathologies confirmed by ultrasonography or MRI; 6.No history of neurological disorders or musculoskeletal diseases; 7.Rotator cuff tear classified as Sugaya grade I–III or Patte stage I on imaging; 8.Tear severity no greater than moderate; NPRS score = 0; 9.Central Sensitization Inventory-9 (CSI-9) score 90. Healthy Control Group Inclusion Criteria 1.No imaging evidence of rotator cuff pathology as confirmed by ultrasonography or MRI;No history of chronic pain;Age- and sex-matched to the C-RCRSP group;
Exclusion criteria
Exclusion criteria: Chronic Rotator Cuff-Related Shoulder Pain (C-RCRSP) Group Exclusion Criteria 1.Presence of significant glenohumeral osteoarthritis, shoulder instability, or a history of shoulder dislocation; 2.History of neurological disorders or neurosurgical procedures, including but not limited to stroke or epilepsy; 3.Presence of systemic diseases that may affect the neuromuscular system; 4.Presence of a cardiac pacemaker, implanted electronic devices, or metallic implants contraindicating MRI or rTMS; 5.Pregnant or breastfeeding women. Asymptomatic Rotator Cuff Tear Group Exclusion Criteria 1.Presence of systemic diseases that may affect the neuromuscular system; 2.Presence of a cardiac pacemaker, implanted electronic devices, or metallic implants contraindicating MRI or rTMS; 3.Pregnant or breastfeeding women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Numeric Pain Rating Scale,NPRS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Constant–Murley Score,CMS;Central Sensitization Inventory-9, CSI-9;Visual Analogue Scale,VAS;Activities of Daily Living,ADL;Brief Pain Inventory-Short Form,BPI-sf;Self-Rating Depression Scale,SDS;Self-Rating Anxiety Scale,SAS;Montreal Cognitive Assessment,MoCA; | — |
Countries
China
Contacts
Public ContactNa Ye
Beijing Hospital
Outcome results
None listed