High-Grade Serous Ovarian Cancer
Conditions
Interventions
Platinum-resistant group and Platinum-sensitive group:None
Sponsors
Harbin Medical University Cancer Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years; 2. Pathologically confirmed high-grade serous ovarian carcinoma (HGSOC); 3. Completion of pre-treatment ultrasound examination with imaging data available for standardized retrospective O-RADS classification; 4. Receipt of standardized postoperative treatment, as documented in medical records; 5. Availability of fresh-frozen or formalin-fixed paraffin-embedded (FFPE) tumor tissue samples in the hospital pathology department; 6. Relatively complete clinical data.
Exclusion criteria
Exclusion criteria: 1. Non-ovarian primary malignancies or non–high-grade serous ovarian carcinoma (HGSOC); 2. Presence of other concomitant malignancies or hematologic disorders; 3. Incomplete imaging data or insufficient tissue sample quality for Raman spectroscopic analysis; 4. Severe missing clinical data or inability to obtain follow-up outcome information.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall Survival;Progression-Free Survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| O-RADS Classification;Raman Spectroscopy Features (peak intensity, peak position, peak ratio, etc.);Serum Biomarkers (e.g., CA125, HE4); | — |
Countries
China
Contacts
Public ContactDai Shaochun
Harbin Medical University Cancer Hospital
Outcome results
None listed