Knee osteoarthritis
Conditions
Interventions
use Compound Eucommia ulmoides Jian Gu Granules alone, or in combination with Compound Eucommia ulmoides Jian Gu Granules on the basis of conventional treatment:None
conventional treatment regimen:None
Sponsors
The Third Affiliated Hospital of Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of the Guidelines for the Diagnosis and Treatment of Osteoarthritis of the Knee (2018 Edition); 2. Exposure group: use compound Eucommia ulmoides bone granules; Non-exposed group: no compound Eucommia ulmoides Jiangu granules were used; 3.Age between 50~75 years old, male or female; 4. Those who voluntarily accept the treatment of this protocol, can adhere to the follow-up according to the doctor's instructions and have good compliance, sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Patients with malignant tumors; 2.Patients with a history of liver disease and kidney disease; 3.Those with allergies and allergies to a variety of drugs; 4.patients undergoing total knee arthroplasty; 5.Patients undergoing unicompartmental arthroplasty; 6.Mentally ill patients, glaucoma patients, women who are lactating, pregnant or have recently intended to become pregnant; 7.Those who are in critical condition and it is difficult to make a definitive evaluation of the safety and effectiveness of drugs; 8.Those who are participating in another clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale for Pain; | — |
Secondary
| Measure | Time frame |
|---|---|
| Western Ontario and McMaster Universities Osteoarthritis Index;Main Symptoms/Signs and TCM Syndrome Graded Quantitative Scoring Scale; | — |
Countries
China
Contacts
Public ContactWeiHeng Chen
The Third Affiliated Hospital of Beijing University of Chinese Medicine
Outcome results
None listed