Painless gastroscopy
Conditions
Interventions
Normal group:Patients were divided into 3 groups based on BMI: normal weight group (18.5 kg/m^2 grade 1 during scope insertion), increase the dose by one gradient for the next patient
conversely, decrease the dose by one gradient. The sequence continued until 8 positive-negative reversal points were achieved.
Super-reconstituted group:Patients were divided into 3 groups based on BMI: overweight group (24 kg/m^2 grade 1 during scope insertion), increase the dose by one gradient for the next patient
Obese group:Patients were divided into 3 groups based on BMI: obese group (28 kg/m^2 <= BMI < 32.5 kg/m^2). A modified Dixon sequential meth
Sponsors
No. 109, Longmian Avenue, Jiangning District, Nanjing City, Jiangsu Province
Eligibility
Sex/Gender
All
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective painless gastroscopy; 2. aged 18-64 years; 3. male or female; 4. 18<=BMI<35kg/m^2; 5. American Society of Anesthesiologists (ASA) anesthesia risk classification I-II.
Exclusion criteria
Exclusion criteria: 1. Gastrointestinal obstruction; 2. Recent upper respiratory tract infection; 3. History of allergy to study drug; 4. Severe cardiopulmonary disease; 5. Severe impairment of liver and kidney function; 6. Obstructive sleep apnea syndrome; 7. Narrowing or surgical history of the upper and middle esophagus; 8. Poorly controlled hypertension, diabetes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ED50; | — |
Countries
China
Contacts
Public ContactLi Yuhong
Sir Run Run Hospital Affiliated to Nanjing Medical University
Outcome results
None listed