Hyperlipemia
Conditions
Interventions
Flaxseed first followed by rice flour:Subjects in the flaxseed-first then rice flour group took flaxseed formula powder twice daily, 30 grams each time to replace staple foods in meals, with an 8-week
Rice flour first then flaxseed group:Subjects in the rice-flaxseed sequential group took rice flour twice daily, 38.5 g each time to replace staple foods in meals, with an intervention period of 8 wee
Sponsors
The Second Affiliated Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Local permanent residents with no plan to move out within the next year, patients with dyslipidemia aged 18 years and above. 2. Normal body temperature and no pulmonary infection. 3. Subjects diagnosed with hyperlipidemia according to the Chinese Guidelines for the Prevention and Treatment of Adult Dyslipidemia (2016 Revised Edition), with triglyceride TG>= 1.70 mmol/L.
Exclusion criteria
Exclusion criteria: 1.Residents aged < 18 years. 2. Subjects taking medications that may affect the results, such as lipid-lowering drugs, appetite suppressants, long-term antibiotics, or taking health supplements that may influence lipid levels, such as fish oil. 3. Subjects with hyperlipidemia induced by medications, such as corticosteroids, ß-blockers, oral contraceptives, interferons, retinoic acid, diuretics. 4. Subjects diagnosed with familial lipoprotein lipase (LPL) deficiency, familial apolipoprotein C-II (ApoC-II) deficiency, familial type III or V hyperlipidemia. 5. Subjects with alcohol dependence or abuse. 6. Subjects with hypothyroidism, Cushing's syndrome, acromegaly, nephrotic syndrome, chronic renal failure, systemic lupus erythematosus, multiple myeloma, or non-alcoholic steatohepatitis (NASH). 7. Subjects allergic to flaxseed or consumed dietary flaxseed supplements in the past six months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Triglycerides; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total cholesterol;Low-density lipoprotein;High-density lipoprotein;Body Composition Analysis; | — |
Countries
China
Contacts
Public ContactZhang Pianhong
The Second Affiliated Hospital of Zhejiang University School of Medicine
Outcome results
None listed