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Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Postoperative Gastrointestinal Function Recovery in Patients Undergoing Colorectal Resection

Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Postoperative Gastrointestinal Function Recovery in Patients Undergoing Colorectal Resection

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2600126046
Enrollment
Unknown
Registered
2026-06-02
Start date
2026-06-05
Completion date
Unknown
Last updated
2026-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal resection

Interventions

The Active transcutaneous Auricular Vagus Nerve Stimulation (taVNS) Group:Based on random grouping results, electrodes were placed on the left ear concha region, and stimulation parameters were adjust
the current was gradually increased within 30 seconds until the patient felt an obvious tingling pain threshold, then decreased to a level slightly below the threshold and maintained. Stimulation was
Sham Stimulation Group:Electrode placement is identical to that in the active group
the current is also increased to the pain threshold within 30 seconds, then adjusted down to a slightly lower threshold, after which the device is kept switched off to simulate sham stimulation. The t

Sponsors

The First People's Hospital of Changde City
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. ASA physical status I–III; 2. Aged between 25 and 75 years; 3. No history of previous abdominal surgery; 4. Voluntary participation and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Conversion from laparoscopic surgery to laparotomy; 2. Inability to comply with trial requirements; 3. Previous history of severe vagal reflex (systolic blood pressure decreased by >30% from baseline, heart rate 30 kg/m².

Design outcomes

Primary

MeasureTime frame
Time to first postoperative flatus (hours);

Secondary

MeasureTime frame
HRV analysis;Time to first defecation;The incidence of postoperative nausea and vomiting;Total perioperative opioid consumption (converted to morphine equivalents);Total length of hospital stay;inflammatory markers;

Countries

China

Contacts

Public ContactWang Xianxue

The First People's Hospital of Changde City

wxxxzyxy2013@163.com+86 159 7366 6202

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026