Senile depression
Conditions
Interventions
Aerobic exercise + rTMS combined treatment group:Aerobic exercise combined with transcranial magnetic stimulation
Conventional group:antidepressant medication
Sponsors
The Fourth People's Hospital of Lianyungang
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age >= 60 years; 2. Physical and laboratory examinations are normal; 3. Meets the relevant diagnostic criteria of the International Classification of Diseases, 10th Revision (ICD-10) for mental and behavioral disorders; 4. HAMD-17 score >= 17; 5. Patient and family agree and sign the informed consent form; 6. Normal motor function and no contraindications for transcranial magnetic stimulation treatment.
Exclusion criteria
Exclusion criteria: 1. Individuals with severe dysfunction of the heart, liver, or kidneys; 2. Individuals with organic brain diseases or those who have undergone cranial surgery; 3. Individuals with other types of mental illnesses; 4. Individuals with self-harm or suicidal tendencies; 5. Individuals with visual or hearing impairments who cannot participate in the questionnaire survey; 6. Individuals with epilepsy; 7. Individuals who do not cooperate with the intervention.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| motor evoked potential (MEP);Hamilton Depression Scale, HAMD-17 ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pittsburgh sleep quality index, PSQI ;36-item Short-Form, SF-36;Montreal Cognitive Assessment, MoCA ;Hamilton Anxiety Scale, HAMA; | — |
Countries
China
Contacts
Public ContactFan Xingyue
The Fourth People's Hospital of Lianyungang
Outcome results
None listed