Helicobacter pylori infection
Conditions
Interventions
Patients undergoing repeat treatment based on H. pylori culture or antibiotic susceptibility testing:None
Experimental group:Vonoprazan + Amoxicillin + Minocycline + Bismuth Pectin
Sponsors
The Second Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Helicobacter pylori infection, with previous failed eradication treatment within the past two years, requiring further eradication treatment; 2. Age 18-70 years; 3. Signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients who are non-compliant with treatment; 2. Patients with mental illness or dysfunction of vital organs such as heart, liver, or kidney before admission; 3. Women planning pregnancy, pregnant women, and lactating women; 4. Patients allergic to the drugs used in this study; 5. Patients who have used bismuth preparations or antibacterial drugs within 4 weeks before treatment, or PPIs or H2 receptor antagonists within 2 weeks before treatment; 6. Patients with a history of upper gastrointestinal surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Helicobacter pylori eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse reactions; | — |
Countries
China
Contacts
Public ContactQiao Wang
The Second Affiliated Hospital of Anhui Medical University
Outcome results
None listed