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Association Between Intraoperative Anesthetic Depth Index and Postoperative Delirium in Elderly Patients Undergoing Major Non-Cardiac Surgery: A Multicenter Prospective Cohort Study

Association Between Intraoperative Anesthetic Depth Index and Postoperative Delirium in Elderly Patients Undergoing Major Non-Cardiac Surgery: A Multicenter Prospective Cohort Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600126020
Enrollment
Unknown
Registered
2026-06-02
Start date
2025-09-09
Completion date
Unknown
Last updated
2026-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

Observation group:None

Sponsors

University Town Hospital Affiliated to Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >=60 years old; 2. Patients scheduled for elective non-cardiac major surgery under general anesthesia; 3. The estimated operation duration is no less than 2 hours. 4. Agree to participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.There are neuropsychiatric diseases that may affect electroencephalogram (EEG) monitoring before the operation, such as epilepsy, schizophrenia, etc. 2. Those who are dependent on drug abuse or sedative and analgesic drugs; 3. Those who have delirium before the operation; 4. Those who are unable to communicate due to severe dementia (diagnosed) or T-MoCA score <=18 points before the operation, language disorders or end-stage diseases; 5. Patients who are expected to have their tracheal tubes removed immediately after the operation; 6. Patients who do not use anesthesia depth monitors during the operation.

Design outcomes

Primary

MeasureTime frame
Postoperative delirium;

Secondary

MeasureTime frame
The incidence of delirium during the recovery period;Delayed neurocognitive recovery 30 days after surgery;Adverse event;

Countries

China

Contacts

Public ContactZhang Yanqing

University Town Hospital Affiliated to Chongqing Medical University

800466@hospital.cqmu.edu.cn+86 139 3519 5692

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026