Hepatocellular carcinoma
Conditions
Interventions
regenerative nodule (RN):None
dysplastic nodule (DN):None
hepatocellular carcinoma (HCC):None
Sponsors
The First Affiliated Hospital,Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-80 years; 2. Patients with liver cirrhosis or chronic hepatitis B infection caused by various reasons; 3. Intrahepatic focal lesions with a diameter of 5 mm <= lesion <= 2 cm; 4. Hepatocellular carcinoma must be confirmed by surgical or biopsy histopathology; diagnosis of benign nodules can be based on histopathological diagnosis or Gd-EOB-DTPA-enhanced MRI diagnosis with no changes upon follow-up after six months; 5. Intrahepatic focal lesions should undergo conventional ultrasound, contrast-enhanced ultrasound, elastography examination, and Gd-EOB-DTPA-enhanced MRI or contrast-enhanced CT examination.
Exclusion criteria
Exclusion criteria: 1.(case group and control group) Liver lesions cannot be clearly shown on 2D ultrasound, such as surrounding gas and rib occlusion; 2.Two or more liver lesions appeared in the same CEUS window (case and control group); 3.Non-cirrhotic nodules such as hepatic hemangioma, hepatic cyst, and focal hepatic nodular hyperplasia were diagnosed; 4.(Case group and control group) The lesion underwent local or systemic antitumor therapy; 5.(case group and control group) with other malignancies;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy;Sensitivity;Specificity; | — |
Countries
China
Contacts
Public ContactXu Ming
The First Affiliated Hospital,Sun Yat-sen University
Outcome results
None listed