gastroenteric tumor
Conditions
Interventions
Lumbar multifidus muscle block group on the arcuate ligament:On the basis of routine anesthesia, during the start of the surgery, ultrasound-guided lumbar psoas muscle block on the superior gluteal li
The dexmedetomidine + superior lumbosacral fascia muscle block group:On the basis of routine anesthesia, anesthesia maintenance: add dexmedetomidine at a dose of 0.5 ug/kg/h, and discontinue the drug
before the start of the surgery, perform lumbar paraspinal muscle block on the arcuate ligament under ultrasound guidance (33% ropivacaine 30 mL).
The dexmedetomidine group:On the basis of routine anesthesia, anesthesia maintenance: add dexmedetomidine at a dose of 0.5 ug/kg/h, and discontinue the drug 20 minutes before the end of the surgery.
Control group:Undergo basic general anesthesia
Sponsors
Guangxi Zhuang Autonomous Region People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Patients scheduled for elective laparoscopic radical surgery for gastrointestinal tumors 2.Age >= 60 years old 3.American Society of Anesthesiologists (ASA) physical status classification II to III 4.Body mass index (BMI) 18 to 28 kg/m^2 5. Can effectively communicate and cooperate with medical staff in the assessment of relevant scales and have good compliance. After fully understanding the risks and benefits of the study, the patient voluntarily signed the informed consent form
Exclusion criteria
Exclusion criteria: 1.Contraindications for nerve block: such as infection at the puncture site, preoperative severe coagulation dysfunction, and abnormal anatomical structure. 2.Patients with critical conditions who are unable to undergo postoperative follow-up. 3.Patients with extensive pelvic infiltration or distant organ metastasis exist. 4.Patients with severe organ damage such as liver, heart and kidney dysfunction. 5.Those who are allergic to opioids, opioid-dependent individuals, and those who have taken pain-relieving drugs before surgery; those who refuse to use patient-controlled analgesia (PCA) pumps and those with severe mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rehabilitation quality 24 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Rehabilitation quality 48 hours after surgery;Rehabilitation quality one day before the surgery;Postoperative VAS score;The dosage of sufentanil used during the operation;The amount of remifentanil used during the operation;The amount of propofol used during the operation;The situation of emergency pain relief within 48 hours after the operation;Total number of times the postoperative 48-hour analgesic pump was pressed;procalcitonin(PCT);Interleukin 6(IL-6);ß-endorphin;creatinine;blood urea nitrogen;alanine aminotransferase(ALT);aspartate aminotransferase;Perioperative vital signs;Aldrete awakening score after removal of the tracheal tube;Recovery time;The time for the first postoperative ambulation after discharge;Time of anal gas expulsion;time of operation;length of stay;hospitalization expenses;The incidence of chronic postoperative pain;Adverse reactions within 3 days after the operation; | — |
Countries
China
Contacts
Public ContactGong Zheng
Guangxi Zhuang Autonomous Region People's Hospital
Outcome results
None listed