fracture of the upper extremity
Conditions
Interventions
A group :General anesthesia combined with ultrasound?guided axillary brachial plexus block was performed, using 0.20% ropivacaine for the nerve block.
B group :General anesthesia combined with ultrasound?guided axillary brachial plexus block was performed, using 0.25% ropivacaine for the nerve block.
C group :General anesthesia combined with ultrasound?guided axillary brachial plexus block was performed, using 0.30% ropivacaine for the nerve block.
Sponsors
Children's Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
3 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Aged 3 to 12 years, with no gender restriction, including preschool children (3–6 years) and school-age children (7–12 years); 2. Physical status classification of Grade I–II according to the American Society of Anesthesiologists (ASA), with no serious underlying diseases; 3. Definitive diagnosis of upper extremity fracture (humerus, ulna and radius, etc.), scheduled for open reduction and internal fixation, and the surgical plan requires anesthesia supplemented by ultrasound-guided axillary brachial plexus block; 4. Patient weight ranging from 10 to 50 kg, weight appropriate for age, without severe malnutrition or obesity (BMI within the normal range for age- and gender-matched children); 5. The child’s guardian has full civil capacity, is able to understand the study content, and voluntarily signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Coagulation disorders (prothrombin time and activated partial thromboplastin time outside the normal range) or receiving anticoagulant therapy (such as aspirin, heparin, etc.); 2.Skin infection, ulceration, scarring or deformity at the axillary brachial plexus block puncture site, which may interfere with the puncture procedure; 3.History of allergy to ropivacaine or other amide local anesthetics (such as rash, dyspnea, etc.); 4. Preoperative upper extremity nerve injury, abnormal limb sensation or motor dysfunction (such as cerebral palsy, peripheral neuropathy, etc.); 5. Complicated with severe cardiopulmonary disease, hepatic or renal insufficiency, metabolic diseases (such as diabetes mellitus, thyroid dysfunction), neuromuscular diseases or infectious diseases; 6.Intellectual disability, mental disorders or cognitive dysfunction, unable to cooperate with postoperative pain and motor function assessment; 7. Long-term use of glucocorticoids, analgesic drugs (such as opioids, nonsteroidal anti-inflammatory drugs) or psychotropic drugs; 8.Guardian refuses to sign the informed consent form, or the child (aged 12 years and older) refuses to participate in the study; 9. Temporary change of surgical plan with no need for axillary brachial plexus block, or operation duration exceeding 3 hours (which may affect the evaluation of analgesic effect).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS score ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bromage Modified Bromage Scale Score for Motor Block; | — |
Countries
China
Contacts
Public ContactWang Qian
Children's Hospital of Soochow University
Outcome results
None listed