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Clinical Study on Correction of Corneal Higher-Order Aberrations to Improve Photic Disturbances After Trifocal Intraocular Lens Implantation

Clinical Study on Correction of Corneal Higher-Order Aberrations to Improve Photic Disturbances After Trifocal Intraocular Lens Implantation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2600125977
Enrollment
Unknown
Registered
2026-06-01
Start date
2026-06-01
Completion date
Unknown
Last updated
2026-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Photic disturbance

Interventions

Observation group:None

Sponsors

Hangzhou MSK Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 45 to 75 years old with no gender restriction; 2. Patients who have undergone trifocal intraocular lens implantation for no less than 3 months, with well-recovered operative eyes and no complications such as ocular infection or fundus lesions; 3. Corrected visual acuity at 100% contrast >=1.0; patients complain of poor functional vision after frame lens correction, accompanied by obvious photic disturbance symptoms including glare, halo, and diplopia that interfere with daily life; 4. Presenting abnormal results in total eye higher-order aberration examination, indicating insufficient focal concentration; 5. Patients voluntarily participate in this study, sign informed consent forms, and are able to cooperate with complete follow-up visits and all examinations including visual acuity tests at 100%, 80%, and 40% contrast levels.

Exclusion criteria

Exclusion criteria: 1. Insufficient corneal thickness (central corneal thickness <480 µm) and intolerance to corneal refractive surgery; 2. Presence of other ocular diseases such as corneal lesions, glaucoma, uveitis, and retinopathy that may affect the results of visual quality examination; 3. Systemic diseases including diabetes mellitus, autoimmune diseases, and other disorders that may interfere with ocular recovery; 4. Previous history of corneal surgery or ocular trauma; 5. Subjects unable to cooperate with subjective and objective examinations and follow-up visits.

Design outcomes

Primary

MeasureTime frame
vision;

Secondary

MeasureTime frame
high-order aberrations;Evaluation of Photopic Disturbance Symptoms;

Countries

China

Contacts

Public ContactZhang Jun

Hangzhou MSK Eye Hospital

zhangjun@mskyk.onaliyun.com+86 571 8531 8888

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026