Acute exacerbation of chronic obstructive pulmonary disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged >= 60 years; 2. Meet the diagnostic criteria for acute exacerbation of chronic obstructive pulmonary disease (AECOPD) specified in the Guidelines for the Diagnosis and Treatment of Chronic Obstructive Pulmonary Disease, and hospitalized due to AECOPD; 3. Score >= 4 (mild frailty or above) on the Clinical Frailty Scale (CFS); 4. Clear consciousness, normal verbal communication ability, and ability to cooperate with scale assessments and study interventions; 5. Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with severe cognitive impairment (e.g., Alzheimer's disease) or psychiatric disorders (e.g., schizophrenia, bipolar disorder); 2. Patients with end-stage diseases (e.g., advanced tumors, end-stage renal disease, liver failure) or with an expected survival time of less than 6 months based on clinical assessment; 3. Patients who are participating in other ongoing interventional clinical trials within 3 months prior to the start of this study; 4. Patients with limb dysfunction or severe visual/hearing impairment that prevents them from completing scale assessments; 5. Patients without a fixed contact address/phone number who are expected to be unable to complete the required follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Score difference of the COPD Assessment Test (CAT); | — |
Secondary
| Measure | Time frame |
|---|---|
| 90-day unplanned readmission rate;Score difference of the Chronic Disease Self-Efficacy Scale;Changes in Clinical Frailty Scale (CFS) grades;Score difference of the Morisky Medication Adherence Scale;Incidence of adverse events; | — |
Countries
China
Contacts
Shenshan Medical Center, Sun Yat-sen Memorial Hospital, Sun Yat-sen University