Acute respiratory distress syndrome
Conditions
Interventions
Control Group:Fixed inspiratory flow rate
Experimental Group:Inhalation flow rate setting
Sponsors
Xuanwu Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.According to the new global definition, patients diagnosed with moderate to severe ARDS require mechanical ventilation; 2.Age>18 years old; 3.No gender restrictions; 4.The guardians of the study participants signed the informed consent form for the subjects;
Exclusion criteria
Exclusion criteria: 1.Patients with pneumothorax or significant pleural effusion; 2.Patients with a history of structural lung disease (such as COPD, bronchiectasis); 3.Patients with contraindications for using EIT (such as the presence of pacemakers or automatic implantable defibrillators, wound dressings, or thoracic drainage fluids); 4.Patients who are unable to use an esophageal pressure catheter (such as those with nasal trauma or deviated nasal septum, such as those undergoing esophageal surgery); 5.Pregnancy status;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change in global heterogeneity index (GI) of the patient on the third day compared to the first day.; | — |
Secondary
| Measure | Time frame |
|---|---|
| First attempt at withdrawal mechanical ventilation time;Changes in inflammatory indicators, oxygenation index, and biomarkers on the third and seventh days compared to the first day; | — |
Countries
China
Contacts
Public ContactBo Liu
Xuanwu Hospital Capital Medical University
Outcome results
None listed