Refractory apical periodontitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Age >= 18 years old, permanent dentition. 2.Meet the indications for intentional tooth replantation: refractory apical periodontitis, failed root canal treatment, and inability to undergo re-root canal therapy or apical surgery; completed root development with attachment loss less than 50%. 3.Meet the indications for autogenous tooth transplantation: dentition defect in need of restoration, suitable root morphology of donor teeth (mostly impacted third molars); sufficient bone volume at the recipient site. 4.Patients signed informed consent and were available for follow-up for at least 1 year.
Exclusion criteria
Exclusion criteria: 1.Uncontrolled systemic diseases (hypertension, diabetes mellitus, heart disease, immunosuppression, severe osteoporosis, etc.) and inability to tolerate tooth extraction. 2.Severe periodontitis, extensive alveolar bone resorption, and severe lesions of adjacent teeth. 3.Severe root resorption, root fracture, and unrestorability of the tooth. 4.Pregnancy, extremely poor compliance, and inability to complete regular follow-up. 5.Severe intraoperative complications leading to failure to complete the operation. 6.Presence of adverse factors affecting tooth prognosis, such as smoking, bruxism, malocclusion, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Periodontal Probing Depth (PPD) \Clinical Attachment Loss (CAL);Apical healing status;Tooth survival rate at 1 and 2 years after treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale (VAS) for pain;Postoperative complications;Bone defect repair status; | — |
Countries
China
Contacts
Stomatology Hospital,Zhejiang University School Medicine