Coronary Atherosclerotic Heart Disease
Conditions
Interventions
Observation group:None
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Underwent PCI and had a coronary stent implanted within 12 months (360 days) prior to undergoing non-cardiac surgery. 2. Age >= 65 years (age at the time of PCI and coronary stent implantation is used as the reference). 3. Requires non-cardiac surgery (including elective or emergency surgery) within 12 months (360 days) after PCI for clinical reasons. 4. Has been regularly taking long-term antiplatelet therapy in the perioperative period (including aspirin, indobufen, and/or P2Y12 receptor inhibitors such as clopidogrel, ticagrelor, etc.).
Exclusion criteria
Exclusion criteria: 1. Patients who have been on long-term oral anticoagulant therapy before surgery (such as warfarin or novel oral anticoagulants); 2. Patients with conditions that may seriously affect the assessment of perioperative outcomes, including but not limited to: active bleeding before surgery or known coagulation disorders; stroke events within 30 days before surgery; advanced malignant tumors with an expected survival of less than 1 year; end-stage liver disease (Child-Pugh class C); 3. Patients for whom perioperative antiplatelet and bridging therapy strategies cannot be clearly classified based on past medical records; 4. Patients undergoing surgery under only local anesthesia or simple peripheral nerve blockade, without combined neuraxial or general anesthesia; 5. Patients with missing key study variables (such as perioperative antiplatelet management strategies or major outcome events) exceeding 20%, making reliable analysis impossible.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite endpoint of major adverse cardiovascular and cerebrovascular events (MACCE) occurring during hospitalization; | — |
Secondary
| Measure | Time frame |
|---|---|
| Unplanned reoperation;In-hospital all-cause death;Postoperative length of hospital stay (pLOS);ICU admission status;In-hospital clinically relevant bleeding events; | — |
Countries
China
Contacts
Public ContactChen Lingmin
West China Hospital of Sichuan University
Outcome results
None listed