Benign prostatic hyperplasia, BPH
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Aged 60–89 years; 2.American Society of Anesthesiologists (ASA) physical status class I–III; 3.Scheduled for elective transurethral resection of the prostate (TURP) under spinal anesthesia (SA) with written informed consent obtained.
Exclusion criteria
Exclusion criteria: 1.Contraindications to spinal anesthesia (including infection at the puncture site, blood coagulation disorders or other hemorrhagic diatheses, intracranial hypertension, severe aortic stenosis, severe mitral stenosis, etc.); 2.Patients with pulmonary diseases (chronic obstructive pulmonary disease, interstitial lung disease, etc.) resulting in pulmonary function grade >= 2; 3.Patients with severe hepatic and renal insufficiency; 4.Patients with baseline systolic blood pressure <= 90 mmHg and/or baseline mean arterial pressure <= 60 mmHg; 5.History of previous neurological or psychiatric disorders; 6.Patients in the very high-risk group for hypertension; 7.Primary lower extremity deep venous valvular insufficiency, deep vein thrombosis of the lower extremities, varicose veins of the lower extremities, iliac vein compression syndrome, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The predictive value of CFV diameter and CFVCI for PSH was evaluated using the area under the receiver operating characteristic curve.;Height; | — |
Secondary
| Measure | Time frame |
|---|---|
| Age;Weight;Body mass index;ASA classification;Comorbidities (hypertension, diabetes mellitus, coronary heart disease, etc.);Fluid replacement status from fasting until entering the operating room;Sensory block level;Duration of anesthesia;Duration of surgery;Resuscitative crystalloid fluid infusion;Ephedrine usage;Usage of bupivacaine;Total amount of fluid replacement;The incidence of adverse reactions;Multicollinearity analysis of suspected risk factors;Single factor logistic regression analysis of suspected risk factors for PSH;Multivariate logistic regression analysis of independent risk factors for PSH;Pearson correlation coefficient (r) analysis of the correlation between CFV diameter, CFVCI, and percentage decrease in blood pressure;Conduct a balance test using propensity score matching method and compare the incidence of PSH between the two groups after matching; | — |
Countries
China
Contacts
Affiliated Hospital of North Sichuan Medical College